A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block

NCT ID
NCT07876310
Registry status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Clinica Santa Maria
Conditions
Osteoarthritis, Knee, Postoperative Pain

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Official title: iPACK Block Versus Popliteal Plexus Block for Posterior Analgesia After Primary Total Knee Arthroplasty in Patients Receiving a Continuous Femoral Triangle Block: A Double-Blind Randomized Clinical Trial

Enrollment: 136 participants (Estimated).

What is being studied

  • Procedure: Ultrasound-Guided Continuous Femoral Triangle Block
  • Procedure: Ultrasound-Guided iPACK Block
  • Procedure: Ultrasound-Guided Popliteal Plexus Block

Who may be eligible

Ages
18 Years to 85 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Adults aged 18-85 years. * Scheduled for elective unilateral primary total knee arthroplasty for knee osteoarthritis. * American Society of Anesthesiologists (ASA) physical status I-III. * Ability to understand and use the 0-10 Numeric Rating Scale (NRS) for pain assessment. * Ability to understand and use the intravenous patient-controlled analgesia (PCA) device. * Ability to complete the Quality of Recovery-15 (QoR-15) questionnaire. * Ability to provide written informed consent. Exclusion Criteria: * Revision or bilateral total knee arthroplasty. * Patient refusal or inability to provide informed consent. * Contraindication to peripheral nerve block, including infection at the needle insertion site or clinically significant coagulation abnormalities. * Known allergy or contraindication to the local anesthetics or analgesic medications used in the study protocol. * Pre-existing clinically significant sensory or motor neurological deficit affecting the operative lower limb. * Chronic opioid use or opioid dependence that could interfere with postoperative opioid consumption assessment. * Inability to understand or operate the PCA device. * Cognitive impairment or communication difficulty preventing reliable assessment of pain, motor function, or QoR-15. * Any medical condition that, in the investigator's judgment, would make participation unsafe or interfere with assessment of the study outcomes.

Study locations

No study locations are listed in the registry data.

Study details

Start date
November 1, 2026
Primary completion date
May 1, 2028
Completion date
May 30, 2028
First posted
October 15, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07876310
Registry last updated
October 15, 2026
QualifiedStudies registry data refreshed
October 19, 2026
QualifiedStudies record fetched
October 19, 2026

View NCT07876310 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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