Cryoneurolysis Versus Bipolar Radiofrequency Ablation of Genicular Nerves for Pain Relief in Symptomatic Knee Osteoarthritis

NCT ID
NCT07855367
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
National Cancer Institute, Egypt
Conditions
Bipolar Radiofrequency Ablation, Cryoneurolysis, Genicular Nerves, Knee Osteoarthritis, Pain Relief, Symptomatic

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Ultrasound-Guided Cryoneurolysis Versus Bipolar Radiofrequency Ablation of Genicular Nerves for Pain Relief in Symptomatic Knee Osteoarthritis: A Randomized Controlled Trial

Enrollment: 30 participants (Estimated).

What is being studied

  • Procedure: Bipolar radiofrequency ablation
  • Procedure: Ultrasound-guided cryoneurolysis

Who may be eligible

Ages
40 Years to no maximum
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Age ≥ 40 years * Symptomatic knee osteoarthritis (OA) in bladder cancer patient \[based on American College of Radiology (ACR) criteria\] * Radiological OA (Kellgren-Lawrence grade III-IV) * Chronic knee pain ≥ 3-6 months * Numerical Rating Scale (NRS) ≥ 5 despite conservative treatment * Positive diagnostic genicular nerve block (\>50% pain relief). Exclusion Criteria: * Prior genicular nerve ablation * Coagulopathy * Local infection * Severe deformity * Neuropathic pain syndromes * Uncontrolled comorbidities

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: Egypt

Sample of listed locations

  • Cairo University — Cairo, 12613, Egypt — Recruiting

Study details

Start date
September 15, 2026
Primary completion date
March 15, 2027
Completion date
March 15, 2027
First posted
October 2, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07855367
Registry last updated
October 2, 2026
QualifiedStudies registry data refreshed
October 5, 2026
QualifiedStudies record fetched
October 5, 2026

View NCT07855367 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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