Transcranial Alternating Current Stimulation (tACS) Combined With Cognitive Training in Alzheimer's Disease

NCT ID
NCT07839650
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Conditions
Alzheimer Dementia (AD), Alzheimer Disease (AD), Cognitive Rehabilitation, Transcranial Alternating Current Stimulation

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Interventional Study to Evaluate the Effectiveness of Transcranial Alternating Current Stimulation (tACS) Combined With Cognitive Training on Cognitive Performance in Patients With Alzheimer's Disease

Enrollment: 30 participants (Estimated).

What is being studied

  • Intervention: Behavioral Disciplines and Activities
  • Intervention: Convulsive Therapy
  • Intervention: Electric Stimulation Therapy
  • Intervention: Electroshock
  • Behavioral: Individualized Computerized Memory Training
  • Intervention: Psychiatric Somatic Therapies
  • Intervention: Psychological Techniques
  • Device: Sham Transcranial Alternating Current Stimulation
  • Intervention: Therapeutics
  • Device: Transcranial Alternating Current Stimulation
  • Intervention: Transcranial Direct Current Stimulation

Who may be eligible

Ages
18 Years to no maximum
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: Patients: * Male or female participants aged ≥18 years at the time of signing the informed consent form; * Clinical diagnosis of mild Alzheimer's disease (AD) according to current clinical criteria; * Availability of a caregiver who can assist the participant and who has successfully completed the required training for the use of the device at home. Caregivers: * Male or female caregivers aged ≥18 years; * Compliance with participation in the in-hospital training; * Mini-Mental State Examination (MMSE) score \>27/30. Exclusion Criteria: * Age below that specified in the inclusion criteria; * Inability to understand; * Contraindications to tACS and TMS (e.g., presence of a cardiac pacemaker or metallic implants incompatible with electrical or magnetic fields, history of epilepsy, or current pregnancy, as assessed using the safety questionnaire).

Study locations

2 study locations are listed.

Recruiting site status is explicitly provided for 2 locations; 1 is listed as Recruiting.

Countries: Italy

  • Brescia, Italy: 1

Sample of listed locations

  • IRCCS Istituto Centro San Giovanni Di Dio - Fatebenefratelli — Brescia, Brescia, 25125, Italy — Recruiting
  • IRCCS S. Maria Nascente - Fondazione Don Carlo Gnocchi — Milan, Italy — Not yet recruiting

Study details

Start date
September 16, 2026
Primary completion date
September 1, 2031
Completion date
September 1, 2032
First posted
September 24, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07839650
Registry last updated
September 24, 2026
QualifiedStudies registry data refreshed
September 28, 2026
QualifiedStudies record fetched
September 28, 2026

View NCT07839650 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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