Neurobiology of Pain in Burn Survivors

NCT ID
NCT07824635
Registry status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Spaulding Rehabilitation Hospital
Conditions
Burn, Chronic Pain, Pain Catastrophizing

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Official title: Neurobiology of Pain in Burn Survivors: Identification and Targeting of a Critical Treatment Mechanism

Enrollment: 92 participants (Estimated).

What is being studied

  • Intervention: Behavior Therapy
  • Intervention: Behavioral Disciplines and Activities
  • Behavioral: Cognitive Behavioral Therapy
  • Intervention: Cognitive Behavioral Therapy
  • Behavioral: Pain Education
  • Intervention: Psychotherapy

Who may be eligible

Ages
18 Years to 65 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Previously hospitalized for burn injury * Age 18 to 65 years * Able to provide written informed consent and fluent in English * Living in a community setting * Six (6) months or more post-burn injury * Burn-related pain rated as ≥4 (on a scale of 0-10) over the past week, co-localized with the site of the burn injury Exclusion Criteria: * Comorbid acute pain condition. * Comorbid chronic pain condition that is rated by the participant as more painful than the burn injury pain. * Living in an institution or medical facility. * Pregnant or nursing. * Any psychiatric condition precluding study participation, such as a disorder involving psychosis (e.g., schizophrenia), unmanaged bipolar disorder, or a severe personality disorder. * History of anxiety disorders or significant anxiety symptoms interfering with imaging procedures (e.g., panic). * Contraindication to MRI (e.g., implanted ferrous metal). * History of significant head injury (e.g., with substantial loss of consciousness). * Psychiatric hospitalization in the past 6 months. * Currently participating in therapeutic clinical research trials.

Study locations

No study locations are listed in the registry data.

Study details

Start date
January 1, 2027
Primary completion date
June 1, 2031
Completion date
October 1, 2031
First posted
September 17, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07824635
Registry last updated
September 22, 2026
QualifiedStudies registry data refreshed
September 28, 2026
QualifiedStudies record fetched
September 28, 2026

View NCT07824635 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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