Lumateperone Added to Antidepressant Therapy in Adults With Major Depressive Disorder Experiencing Emotional Blunting
- NCT ID
- NCT07824206
- Registry status
- Not yet recruiting
- Study type
- Not specified in the registry data
- Phase
- Phase 4
- Sponsor
- Future Options Research, LLC
Overview
ClinicalTrials.gov lists this study as Not yet recruiting.
Enrollment: 30 participants (Estimated).
What is being studied
No interventions are listed in the registry data.
Who may be eligible
- Ages
- Not specified in the registry data
- Sex
- Not specified in the registry data
- Healthy volunteers accepted
- No
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria: Diagnosis of major depressive disorder documented in the medical record and confirmed through evaluation by the Principal Investigator using the M.I.N.I., Oxford Depression Questionnaire score of \> 50 (substantial emotional blunting), Response of "yes" to the "gold standard" standardized screening question on emotional blunting developed by Price et al(2012): "Emotional effects vary, but may include, for example, feelingemotionally 'numbed' or 'blunted' in some way; lacking positive emotions or negative emotions; feeling detached from the world around you; or 'just not caring' about things you used to care about. Have you experienced such emotional effects during the last 6 weeks?" -
Exclusion Criteria: Concomitant antipsychotics, Concomitant inhibitors of CYP3A4, Concomitant use of cannabis, Moderate to severe hepatic impairment, Primary diagnosis other than major depressive disorder
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Study locations
1 study location is listed.
Site recruitment status is not specified in the registry data for these locations.
Countries: United States
- Pennsylvania, United States: 1
Sample of listed locations
- Future Options Research — State College, Pennsylvania, 16801, United States — Site recruitment status not specified in the registry data
Study details
- Start date
- September 1, 2026
- Primary completion date
- January 1, 2028
- First posted
- September 17, 2026
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT07824206
- Registry last updated
- September 17, 2026
- QualifiedStudies registry data refreshed
- September 21, 2026
View NCT07824206 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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