The Effect of Nicorandil on Rheumatoid Arthritis Patients

NCT ID
NCT07730723
Registry status
Recruiting
Study type
Not specified in the registry data
Phase
Phase 2 / Phase 3
Sponsor
Ain Shams University

Overview

ClinicalTrials.gov lists this study as Recruiting.

Enrollment: 70 participants (Estimated).

What is being studied

No interventions are listed in the registry data.

Who may be eligible

Ages
Not specified in the registry data
Sex
Not specified in the registry data
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Adult (≥18 years). * Confirmed diagnosis with RA according to ACR/EULAR 2010 criteria. * Moderate to severe disease activity (DAS-28 ˃ 3.2). * Stable on conventional treatment for at least 3 months. * Adequate kidney and liver function. Exclusion Criteria: * Other autoimmune diseases * Poor patient compliance * Malignancy or history of malignancy * Pregnancy or lactation. * Patients receiving bDMARDs or tsDMARDs. * Hypersensitivity to nicorandil. * Left ventricular heart failure or severe hypotension (SBP ˂100 mmHg). * History of cardiogenic shock. * History or active gastric ulcer. * Use of drugs contraindicated with nicorandil (e.g., sildenafil, tadalafil, vardenafil, tricyclic antidepressants, or guanyl cyclase).

Study locations

1 study location is listed.

Site recruitment status is not specified in the registry data for these locations.

Countries: Egypt

  • Abbasia, Egypt: 1

Sample of listed locations

  • Ain Shams University Hospitals — Cairo, Abbasia, Egypt — Site recruitment status not specified in the registry data

Study details

Start date
September 6, 2026
Primary completion date
July 1, 2027
First posted
July 28, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07730723
Registry last updated
September 16, 2026
QualifiedStudies registry data refreshed
September 21, 2026

View NCT07730723 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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