Accelerated iTBS for PTSD and Depression

NCT ID
NCT07682207
Registry status
Recruiting
Study type
Not specified in the registry data
Phase
Not applicable
Sponsor
Lawson Research Institute of St. Joseph's

Overview

ClinicalTrials.gov lists this study as Recruiting.

Enrollment: 16 participants (Estimated).

What is being studied

No interventions are listed in the registry data.

Who may be eligible

Ages
Not specified in the registry data
Sex
Not specified in the registry data
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Adults aged 18 years or older. * Current post-traumatic stress disorder (PTSD) and current major depressive disorder (MDD), confirmed by a structured diagnostic interview (e.g., MINI 6.0 using the PTSD and MDD modules). * Minimum symptom severity at baseline: HAMD-17 score ≥14 (moderate depression) and/or PCL-5 score ≥33 (probable PTSD). * On a stable pharmacologic and/or psychotherapeutic regimen for at least 4 weeks prior to baseline, and willing to maintain stability during the treatment phase, unless medically necessary. * Capacity to provide informed consent and comply with study procedures and visits at St. Joseph's Health Care, London/Parkwood Institute. * Sufficient English proficiency to complete consent and study assessments. Exclusion Criteria: * Neurologic or device-related risks, including seizure history, traumatic brain injury with loss of consciousness greater than 5 minutes, major neurologic illness, or metal/electronic implants contraindicated for transcranial magnetic stimulation. * Psychiatric or substance-related risks, including current psychotic disorder, acute mania, diagnosis of Bipolar I or Bipolar II disorder, recent substance use disorder, or imminent suicide risk. * Medical or medication-related risks, including unstable severe illness, high-risk medications, hearing impairment, unwillingness to use ear protection, or prior non-response to an adequate course of theta burst stimulation for the current depression/PTSD episode. * Enrollment in another interventional trial. * Inability to comply with the study schedule.

Study locations

1 study location is listed.

Site recruitment status is not specified in the registry data for these locations.

Countries: Canada

  • Ontario, Canada: 1

Sample of listed locations

  • St. Joseph's Health Care London, Parkwood Institute Mental Health Care Building — London, Ontario, N6C 0A7, Canada — Site recruitment status not specified in the registry data

Study details

Start date
September 1, 2026
Primary completion date
June 1, 2027
First posted
July 2, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07682207
Registry last updated
September 18, 2026
QualifiedStudies registry data refreshed
September 21, 2026

View NCT07682207 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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