Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement

NCT ID
NCT07629388
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Conditions
Pain After Total Knee Arthroplasty, Pain Management

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Comparative Study Assessing the Efficacy of a Combined Distal Femoral Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty (TKA)

Enrollment: 240 participants (Estimated).

What is being studied

  • Procedure: Combined distal femoral nerve block
  • Procedure: Saphenous nerve block alone
  • Procedure: Standard perioperative care in both groups

Who may be eligible

Ages
18 Years to no maximum
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Adult patients aged over 18 years. * Scheduled for total knee arthroplasty with multimodal analgesia. * Affiliated with or benefiting from a social security system. * Able to understand the study information and provide written informed consent. Exclusion Criteria: * Emergency surgery. * Weight under 50 kg. * Body mass index over 40 kg/m². * Contraindication to nefopam, non-steroidal anti-inflammatory drugs, local anesthetics, or morphine. * Preoperative opioid use. * Antidepressant or gabapentinoid treatment. * Other planned surgical or medical procedures during the study period. * Participation in another clinical trial, or currently in an exclusion period from another trial. * Inability to understand study information for linguistic, psychological, cognitive, or literacy reasons. * Pregnancy, possible pregnancy without effective contraception, or breastfeeding. * Protected adults, including those under guardianship, curatorship, legal protection, detention, or otherwise unable to give informed consent.

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: France

Sample of listed locations

  • Hôpital privé Dijon Bourgogne — Dijon, 21000, France — Recruiting

Study details

Start date
May 26, 2026
Primary completion date
May 25, 2027
Completion date
May 25, 2027
First posted
June 5, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07629388
Registry last updated
October 5, 2026
QualifiedStudies registry data refreshed
October 12, 2026
QualifiedStudies record fetched
October 12, 2026

View NCT07629388 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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