An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

NCT ID
NCT07620392
Registry status
Recruiting
Study type
Interventional
Phase
Phase 2
Sponsor
Hoffmann-La Roche
Conditions
Rheumatoid Arthritis

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: An Extension Study to Evaluate the Long-term Safety and Efficacy of Afimkibart (RO7790121) in Patients With Rheumatoid Arthritis Who Participated in Previous Afimkibart Clinical Trials

Enrollment: 120 participants (Estimated).

What is being studied

  • Drug: Afimkibart

Who may be eligible

Ages
18 Years to no maximum
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Completed the treatment period of the parent study * Agreement to adhere to the contraception requirements * Continued to be evaluated at the follow-up visit of the parent study and achieved improvement in the SJC66/TJC68 relative to baseline Exclusion Criteria: * Withdrawal of consent and/or premature discontinuation from parent study * Any permanent discontinuation of study drug in parent study * Use of a prohibited therapy during the parent study * Evidence of any new or uncontrolled concomitant disease that, in the investigator's judgment, would preclude participant participation in the trial

Study locations

10 study locations are listed.

Recruiting site status is explicitly provided for 10 locations; 10 are listed as Recruiting.

Countries: Poland, United States

  • Masovian Voivodeship, Poland: 1
  • Florida, United States: 1
  • Louisiana, United States: 1
  • Texas, United States: 2

Sample of listed locations

  • Centrum Medyczne Reuma Park — Warsaw, Masovian Voivodeship, 02-665, Poland — Recruiting
  • Nzoz Bif-Med — Bytom, 41-902, Poland — Recruiting
  • Centrum Kliniczno-Badawcze J. Brzezicki, B. Górnikiewicz-Brzezicka Lekarze Spó?ka Partne — Elblag, 82-300, Poland — Recruiting
  • Zespol Poradni Specjalistycznych REUMED filia nr 1 Wallenroda — Lublin, 20-607, Poland — Recruiting
  • Twoja Przychodnia NCM — Nowa Sól, 67-100, Poland — Recruiting
  • Reumatop Grzegorz Rozumek Karin Pistorius Spolka Jawna — Wroclaw, 52-210, Poland — Recruiting
  • West Broward Rheumatology Associates, Inc. — Tamarac, Florida, 33321, United States — Recruiting
  • Accurate Clinical Research Inc. — Lake Charles, Louisiana, 70605, United States — Recruiting
  • Accurate Clinical Management LLC — Houston, Texas, 77089, United States — Recruiting
  • DM Clinical Research — Tomball, Texas, 77375, United States — Recruiting

Study details

Start date
June 3, 2026
Primary completion date
July 8, 2033
Completion date
July 8, 2033
First posted
June 2, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07620392
Registry last updated
September 18, 2026
QualifiedStudies registry data refreshed
October 2, 2026
QualifiedStudies record fetched
October 2, 2026

View NCT07620392 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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