Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy

NCT ID
NCT07569549
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Uppsala University
Conditions
Basal Thumb Osteoartrithis, Carpometacarpal (CMC) Joint Arthritis, Thumb Carpometacarpal Joint Osteoarthritis, Thumb Osteoarthritis

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: BASTION - BASe of Thumb Osteoarthritis Management Non-inferiority Trial: Surgical Treatment of First Carpometacarpal Joint Osteoarthritis: A Comparison Between Joint Replacement and Trapeziectomy

Enrollment: 84 participants (Estimated).

What is being studied

  • Device: Implantation of trapeziometacarpal prosthesis
  • Procedure: Trapeziectomy with Capsuloplasty

Who may be eligible

Ages
40 Years to 80 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Age 40-80 years at inclusion * CMC-joint osteoarthritis grade 1-3 (Eaton-Littler classification) * Rest pain or pain reducing hand function with indication for surgery * Insufficient relief from non-operative treatment for ≥3 months (orthosis, OTC analgesics, cortisone injection) * Eligible for both prosthesis and trapezectomy per including surgeon * Non-smoker or complete smoking cessation ≥6 weeks prior to surgery Exclusion Criteria: * Previous surgery to thumb base or STT-joint * Ongoing general chronic pain condition or other pain in the same hand predominant over the thumb base pain. * Dementia or cognitive impairment * Trapezium height \<7 mm on plain radiograph * Active smoker * Osteoarthritis grade 4 (Eaton-Littler)

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: Sweden

Sample of listed locations

  • Department of Handsurgery, Uppsala University Hospital — Uppsala, Sweden — Recruiting

Study details

Start date
September 4, 2026
Primary completion date
May 1, 2030
Completion date
March 1, 2038
First posted
May 6, 2026
Collaborators
Uppsala County Council, Sweden

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07569549
Registry last updated
October 9, 2026
QualifiedStudies registry data refreshed
October 12, 2026
QualifiedStudies record fetched
October 12, 2026

View NCT07569549 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

About joining clinical research

Find clinical trials you may match with

QualifiedStudies can help you search for research opportunities related to your health. Availability of this specific study through QualifiedStudies has not been established.

Find clinical trials you may match with | Arthritis studies | Clinical trial FAQ