Evaluating Avive+ Soft Tissue Matrix for Prevention of Superficial Radial Nerve Morbidity Following Radial Forearm Free Flap Harvest

NCT ID
NCT07558096
Registry status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
University of Alabama at Birmingham
Conditions
Head and Neck Cancer (H&N)

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Official title: A Randomized Controlled Pilot Study Evaluating Avive+ Soft Tissue Matrix for Prevention of Superficial Radial Nerve Morbidity Following Radial Forearm Free Flap Harvest

Enrollment: 80 participants (Estimated).

What is being studied

  • Procedure: Avive+ Intervention
  • Procedure: Standard Closure (Control)

Who may be eligible

Ages
18 Years to no maximum
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Age ≥ 18 years * Undergoing RFFF for head and neck reconstruction * Treated at University of Alabama at Birmingham * Able to provide informed consent * Willing to comply with follow-up Exclusion Criteria: * Reconstruction using a non-RFFF free flap * Pre-existing ipsilateral radial nerve neuropathy * Prior ipsilateral forearm surgery affecting nerve anatomy * Active donor-site infection * Severe peripheral vascular disease * Inability to complete follow-up

Study locations

1 study location is listed.

Site recruitment status is not specified in the registry data for these locations.

Countries: United States

  • Alabama, United States: 1

Sample of listed locations

  • University of Alabama at Birmingham — Birmingham, Alabama, 35294, United States — Site recruitment status not specified in the registry data

Study details

Start date
November 1, 2026
Primary completion date
December 1, 2029
Completion date
December 1, 2029
First posted
April 30, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07558096
Registry last updated
September 25, 2026
QualifiedStudies registry data refreshed
October 5, 2026
QualifiedStudies record fetched
October 5, 2026

View NCT07558096 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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