ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive Disorder
- NCT ID
- NCT07474974
- Registry status
- Recruiting
- Study type
- Not specified in the registry data
- Phase
- Not applicable
- Sponsor
- Polytechnic Institute of Porto
Overview
ClinicalTrials.gov lists this study as Recruiting.
Enrollment: 44 participants (Estimated).
What is being studied
No interventions are listed in the registry data.
Who may be eligible
- Ages
- Not specified in the registry data
- Sex
- Not specified in the registry data
- Healthy volunteers accepted
- No
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
* Diagnosis of MDD, confirmed via the structured clinical interview;
* TRD type;
* Age between 18-65 years;
* Visual acuity of 20/32 or better.
Exclusion Criteria:
* Prior rTMS treatment;
* Contraindications for TMS;
* Psychiatric disorders other than MDD;
* Systemic diseases affecting the eyes (e.g., diabetes mellitus);
* Ocular conditions;
* Head injuries causing loss of consciousness;
* Current or past alcohol/substance dependence within 6 months;
* Neurodegenerative diseases;
* Major neurological illnesses;
* Use of medications affecting iris mechanics or the autonomic nervous system.
Study locations
1 study location is listed.
Site recruitment status is not specified in the registry data for these locations.
Countries: Portugal
- Porto District, Portugal: 1
Sample of listed locations
- RISE-Health, Center for Translational Health and Medical Biotechnology Research (TBIO), School of Health, Polytechnic of Porto — Porto, Porto District, 4200-072, Portugal — Site recruitment status not specified in the registry data
Study details
- Start date
- March 15, 2026
- Primary completion date
- April 30, 2027
- First posted
- March 16, 2026
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT07474974
- Registry last updated
- September 18, 2026
- QualifiedStudies registry data refreshed
- September 21, 2026
View NCT07474974 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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