Effects of Probiotic Supplementation on Stress and Anxiety in Students

NCT ID
NCT07470645
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Nordic Biotic Sp. z o.o.
Conditions
Anxiety, Gastro-intestinal Symptoms in Healthy Subjects, Sleep, Stress

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: The Efficacy of Probiotic Supplementation in Reducing Stress and Anxiety: A Randomized, Placebo-Controlled Study in Healthy Students During the Examination Period

Enrollment: 200 participants (Estimated).

What is being studied

  • Intervention: Diet, Food, and Nutrition
  • Intervention: Dietary Supplements
  • Intervention: Food
  • Intervention: Food and Beverages
  • Intervention: Physiological Phenomena
  • Other: Placebo
  • Intervention: Probiotics
  • Dietary supplement: Probiotics

Who may be eligible

Ages
18 Years to 40 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Male or female students aged 18-40 years * At least moderate stress (DASS-21 Stress score ≥10) * Mild anxiety (DASS-21 Anxiety score 6-13) * No clinical depression (DASS-21 Depression score ≤9) * Willingness to maintain usual diet, physical activity, and intake of caffeinated beverages during the study * Written informed consent Exclusion Criteria: * Irritable bowel syndrome (Rome IV criteria) or any chronic intestinal disease (including celiac disease) * Known food allergies, immunodeficiency disorders, or immunosuppressive treatment * Antibiotic use within 4 weeks prior to screening * Any psychiatric illness within the past 5 years * Any malignant disease or autoimmune or allergic diseases (e.g., atopic dermatitis, asthma) * Use of systemic psychotropic medications or steroids; use of topical corticosteroid creams within 4 weeks prior to screening * Pregnancy, breastfeeding, or plans to become pregnant during the study * Probiotic or prebiotic consumption or planned dietary changes within 4 weeks prior to screening * Heavy caffeine consumption (\>4 cups of 300 mL coffee per day) * Drug or alcohol addiction or regular use of recreational drugs * Smoking more than 10 cigarettes per day

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: Poland

Sample of listed locations

  • University of Lublin, Faculty of Health Sciences — Lublin, Poland — Recruiting

Study details

Start date
April 20, 2026
Primary completion date
July 15, 2026
Completion date
October 15, 2026
First posted
March 13, 2026
Collaborators
Wörwag Pharma GmbH & Co. KG

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07470645
Registry last updated
September 25, 2026
QualifiedStudies registry data refreshed
October 5, 2026
QualifiedStudies record fetched
October 5, 2026

View NCT07470645 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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