A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
- NCT ID
- NCT07465224
- Registry status
- Recruiting
- Study type
- Not specified in the registry data
- Phase
- Phase 2
- Sponsor
- Alnylam Pharmaceuticals
Overview
ClinicalTrials.gov lists this study as Recruiting.
Enrollment: 24 participants (Estimated).
What is being studied
No interventions are listed in the registry data.
Who may be eligible
- Ages
- Not specified in the registry data
- Sex
- Not specified in the registry data
- Healthy volunteers accepted
- No
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
* Is an adult patient with a confirmed diagnosis of T2DM
* Has a body mass index (BMI) of ≥23 kg/m\^2 to ≤39.9 kg/m\^2
* Has a hemoglobin A1c (HbA1c) ≥6.5% to \<10.5%
* Is on a stable dose of metformin, sodium-glucose cotransporter 2 inhibitor (SGLT2i), or dipeptidyl peptidase-4 inhibitor (DPP4i)
Exclusion Criteria:
* Has any clinically significant concomitant disease, medical condition, or abnormal laboratory finding that could compromise participant safety or confound interpretation of study results
* Receiving therapies known to interfere with glucose or insulin metabolism other than current treatment for T2DM or birth control methods
Note: other protocol defined inclusion/exclusion criteria apply
Study locations
1 study location is listed.
Site recruitment status is not specified in the registry data for these locations.
Countries: United States
- California, United States: 1
Sample of listed locations
- Clinical Trial Site — Chula Vista, California, 91911, United States — Site recruitment status not specified in the registry data
Study details
- Start date
- January 15, 2026
- Primary completion date
- May 28, 2027
- First posted
- March 11, 2026
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT07465224
- Registry last updated
- September 16, 2026
- QualifiedStudies registry data refreshed
- September 21, 2026
View NCT07465224 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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