High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults

NCT ID
NCT07444554
Registry status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
University of Illinois at Chicago
Conditions
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Official title: Training the Aging Brain Through Speed: Examining Cerebrovascular Adaptations Associated With Motor-Cognitive Performance Following High-Velocity Resistance Training in Older Adults at Risk for AD/ADRD

Enrollment: 60 participants (Estimated).

What is being studied

  • Intervention: Aftercare
  • Intervention: Continuity of Patient Care
  • Intervention: Exercise
  • Intervention: Exercise Therapy
  • Behavioral: High-Velocity Resistance Training
  • Intervention: Motor Activity
  • Intervention: Movement
  • Intervention: Musculoskeletal and Neural Physiological Phenomena
  • Intervention: Musculoskeletal Physiological Phenomena
  • Intervention: Patient Care
  • Intervention: Physical Conditioning, Human
  • Intervention: Physical Therapy Modalities
  • Intervention: Rehabilitation
  • Intervention: Resistance Training
  • Intervention: Therapeutics

Who may be eligible

Ages
60 Years to 79 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Age 60 to 79 years * Able to walk on a treadmill at a comfortable, self-selected pace for at least 30 minutes with short breaks * Has at least one vascular risk factor (such as high blood pressure or high cholesterol) * Has a first-degree family history of dementia or self-reported concerns about memory or thinking * Fluent in English * Willing and able to provide written informed consent * Cleared to participate in supervised resistance training based on physical activity screening and, if required, physician clearance Exclusion Criteria: * Diagnosis of Alzheimer disease, other dementia, stroke, Parkinson disease, multiple sclerosis, or another major neurological disorder * Unstable cardiovascular disease (such as recent heart attack, unstable chest pain, or uncontrolled abnormal heart rhythm) * Uncontrolled high blood pressure * Major psychiatric illness that would interfere with participation * Medical condition that makes moderate-to-high intensity resistance training unsafe * Current participation in structured high-intensity resistance training * Any medical condition that, in the opinion of the study investigator, would increase risk during participation

Study locations

No study locations are listed in the registry data.

Study details

Start date
December 1, 2026
Primary completion date
May 1, 2028
Completion date
May 1, 2028
First posted
March 3, 2026
Collaborators
National Institute on Aging (NIA)

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07444554
Registry last updated
October 14, 2026
QualifiedStudies registry data refreshed
October 19, 2026
QualifiedStudies record fetched
October 19, 2026

View NCT07444554 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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