Accelerated and Extended-iTBS Targeting Inhibitory Control in Veterans With ADHD

NCT ID
NCT07442058
Registry status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
VA Office of Research and Development
Conditions
Attention Deficit Disorder With Hyperactivity

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Official title: ACHIEVE: Accelerated and Extended-rTMS to Heighten Inhibitory Control Engagement in Veterans

Enrollment: 35 participants (Estimated).

What is being studied

  • Device: Intermittent Theta-Burst Stimulation
  • Device: Sham Stimulation

Who may be eligible

Ages
18 Years to 65 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Diagnosis of ADHD predominantly hyperactive-impulsive or combined, as outlined in the DSM-5-TR criteria * Maintenance of clinical symptoms despite receiving stable treatment for a minimum of 6 weeks before the study procedures * Capability to comprehend and provide informed consent * For safety reasons, participants must meet established screening criteria to ensure safety during Magnetic Resonance Imaging (MRI) scans * This precaution is taken due to the novel application of iTBS in this specific population, as MRI involves exposure to magnetic fields similar in intensity to those emitted from the stimulation coil * As such, participants must not have the following, unless the devices are MRI-safe: * cardiac pacemaker * implanted devices (such as deep brain stimulators) * metal in the brain * cervical spinal cord, or upper thoracic spinal cord level * In addition, eligible Veterans must also be able and willing to comply with all study procedures and visits * Throughout the study, pharmacologic and psychotherapeutic regimens will tentatively remain unchanged Exclusion Criteria: * Primary psychotic disorders, bipolar I disorder, ongoing severe substance use disorders, or active suicidality * Non-MRI safe cardiac pacemakers, implanted devices, or metallic implants at the upper thoracic spine level or higher * Any of the Transcranial Magnetic Stimulation (TMS) specific exclusion criteria, including: * pregnancy * lactation * planning pregnancy during period of study * history of moderate or severe traumatic brain injury * active unstable medical conditions * CNS tumors * seizures * cerebrovascular disease * other severe neurological disorders * Additional exclusion criteria include the presence of any other condition or circumstance that, as determined by the investigator team, has the potential to prevent study completion or introduce confounding effects in outcome assessments

Study locations

1 study location is listed.

Site recruitment status is not specified in the registry data for these locations.

Countries: United States

  • Rhode Island, United States: 1

Sample of listed locations

  • Providence VA Medical Center, Providence, RI — Providence, Rhode Island, 02908-4734, United States — Site recruitment status not specified in the registry data

Study details

Start date
October 1, 2026
Primary completion date
October 1, 2027
Completion date
July 1, 2028
First posted
March 2, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07442058
Registry last updated
July 22, 2026
QualifiedStudies registry data refreshed
September 28, 2026
QualifiedStudies record fetched
September 28, 2026

View NCT07442058 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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