Feasibility of Modulating Cognitive Control in OCD

NCT ID
NCT07419009
Registry status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Dartmouth-Hitchcock Medical Center
Conditions
Obsessive-Compulsive Disorder (OCD)

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Official title: Evaluating Frontal Pole as a Window to Modulation of Cognitive Control in OCD

Enrollment: 12 participants (Estimated).

What is being studied

  • Device: continuous theta-burst transcranial magnetic stimulation (cTBS)

Who may be eligible

Ages
18 Years to 60 Years
Sex
All
Healthy volunteers accepted
Yes

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Current primary DSM-5 OCD diagnosis and current Y-BOCS total score of ≥16 (OCD group, only) or no current diagnosis of an emotional disorder, and no known history of OCD, PTSD, anxiety disorder(s), or recurrent major depressive disorder (Healthy participant group, only) * 18-60 years of age * ability to speak, read, write, and understand English sufficiently well to complete study procedures and provide informed consent * psychotherapy and/or psychiatric medication use remain stable for 6 weeks prior to study entry Exclusion Criteria: * Presence of current psychiatric diagnosis (healthy control group, only) * active substance use disorder * history of mania or hypomania, or lifetime presence of significant psychotic symptoms * active suicidal or homicidal ideation * use of medications known to reduce seizure threshold (e.g., stimulants) * organic brain disease or injury representing a contraindication to TMS * any health problems that would interfere with safe and/or practical study participation, including contraindications to TMS (e.g., seizure disorder, presence of metal hardware that would come in close contact with the discharging coil) * current pregnancy or planning to become pregnant during the study period

Study locations

No study locations are listed in the registry data.

Study details

Start date
November 1, 2026
Primary completion date
September 30, 2027
Completion date
September 30, 2027
First posted
February 18, 2026

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07419009
Registry last updated
October 2, 2026
QualifiedStudies registry data refreshed
October 5, 2026
QualifiedStudies record fetched
October 5, 2026

View NCT07419009 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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