Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)

NCT ID
NCT07347028
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Beijing Tiantan Hospital
Conditions
Cervicogenic Headache, Chronic Musculoskeletal Pain, Migraine, Myofascial Trigger Points

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Musculoskeletal Pain(CMP), Chronic Migraine and Cervicogenic Headache

Enrollment: 238 participants (Estimated).

What is being studied

  • Intervention: Drug Administration Routes
  • Intervention: Drug Therapy
  • Intervention: Injections
  • Procedure: Intra-articular(IA) Injection
  • Procedure: MTrPs Injection
  • Intervention: Therapeutics

Who may be eligible

Ages
45 Years to no maximum
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Diagnosis of knee osteoarthritis with radiographic evidence of osteoarthritis (Kellgren-Lawrence grade 1-4) confirmed by at least two orthopedic surgeons, pain specialists, or general practitioners, with physical examination confirming at least one myofascial trigger point; * Disease duration exceeding 3 months; * Age ≥ 45 years; * Numerical Rating Scale (NRS) score ≥ 3 points despite prior conservative pharmacological treatment; * Signed informed consent form. Exclusion Criteria: * History of allergy to trial medications such as corticosteroids; * Alcohol abuse; long-term use of opioids (exceeding 2 weeks or more than 3 days per week for over 1 month); suspected use of sedative or analgesic medications; patients on long-term steroid therapy; * Severe neurological disorders, significant hepatic or renal dysfunction, heart failure, coagulation abnormalities, gastric ulcer, diabetes, inflammatory rheumatic diseases, etc.; * Intra-articular injection within the past 6 months or planned joint replacement surgery; * Inability to use pain assessment scales; * Presence of local or systemic infection; * Pregnant or lactating patients.

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: China

  • Beijing Municipality, China: 1

Sample of listed locations

  • Beijing Tiantan Hospital — Beijing, Beijing Municipality, 100070, China — Recruiting

Study details

Start date
October 1, 2025
Primary completion date
December 1, 2026
Completion date
January 1, 2027
First posted
January 16, 2026
Collaborators
Beijing Aerospace General Hospital, Beijing Jianjia Rehabilitation Hospital, Renmin Hospital of Wuhan University, The First Affiliated Hospital of Nanchang University, The Second Affiliated Hospital of Harbin Medical University, Yangyuan Youyi Hospital

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07347028
Registry last updated
October 8, 2026
QualifiedStudies registry data refreshed
October 12, 2026
QualifiedStudies record fetched
October 12, 2026

View NCT07347028 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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