Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis

NCT ID
NCT07274124
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Medipol University
Conditions
Rheumatic Diseases, Rheumatoid Arthritis (RA)

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Comparison of the Effects of Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis

Enrollment: 42 participants (Estimated).

What is being studied

  • Intervention: Electric Stimulation Therapy
  • Other: Pain Neuroscience Education
  • Other: Structured Exercises
  • Intervention: Therapeutics
  • Other: Vagal Nerve Stimulation
  • Intervention: Vagus Nerve Stimulation

Who may be eligible

Ages
20 Years to 65 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Individuals who were diagnosed with RA at least one year ago, * More than score 2.6 in DAS28, * Ages of 20 and 65, * Have been experiencing pain for three months or more, * Score 24 or higher on the Mini Mental State Examination (MMSE), and can follow instructions will be included in the study. Exclusion Criteria: * Individuals under 20 years of age, * Reporting acute pain or pain from injury, * Having a history of surgery within the last year, * Remission in DAS28, * Patients whose medication was changed, * Having a score of \<24 on the MMSE, * Having any of the cerebrovascular disease, cardiovascular disease, symptomatic coronary artery disease, myocardial infarction, congestive heart failure, or uncontrolled hyper/hypotension, * History of vagotomy surgery, or having an implanted electrical/neurostimulator device will not be included in the study.

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: Turkey (Türkiye)

  • Fatih, Turkey (Türkiye): 1

Sample of listed locations

  • Cerrahpaşa Faculty of Medicine Hospital — Istanbul, Fatih, Turkey (Türkiye) — Recruiting

Study details

Start date
February 18, 2026
Primary completion date
May 1, 2027
Completion date
July 1, 2027
First posted
December 10, 2025
Collaborators
Istanbul University - Cerrahpasa

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07274124
Registry last updated
October 9, 2026
QualifiedStudies registry data refreshed
October 12, 2026
QualifiedStudies record fetched
October 12, 2026

View NCT07274124 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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