Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANT

NCT ID
NCT07158567
Registry status
Not yet recruiting
Study type
Not specified in the registry data
Phase
Phase 3
Sponsor
VA Office of Research and Development

Overview

ClinicalTrials.gov lists this study as Not yet recruiting.

Enrollment: 213 participants (Estimated).

What is being studied

No interventions are listed in the registry data.

Who may be eligible

Ages
Not specified in the registry data
Sex
Not specified in the registry data
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * 1 month stability in pain management strategies * Can read and speak English * Able to participate in strengthening, stretching, range of motion exercise via yoga as determined by study physician * Chronic Low Back Pain (CLBP): pain in the low back that persists for \>6 months and is of moderate to severe intensity with a score of \>5 on specific items on the BPI demonstrating disability of at least 20% on the Oswestry Disability Index (ODI) Exclusion Criteria: * Contraindications to combined intermittent theta burst (iTBS)/transcranial magnetic stimulation (TMS), (e.g., epilepsy, psychotic spectrum disorders \[i.e. bipolar, schizophrenia\], history of anoxic brain injury) * Moderate to severe heart disease * Contraindications to MRI (e.g., claustrophobia, implanted ferromagnetic device such as pacemaker or cardiac defibrillator) * Pain believed to be associated with cardiac or ischemic conditions * Epilepsy, active seizure disorder, personal history of a seizure or individuals with a family history of epilepsy or seizure in a first degree relative * Current prescription of psychostimulants (e.g., amphetamines), anticholinergics, tricyclic antidepressants, and antipsychotics or other medications that may increase their risk of having seizures * Intracranial lesion * History of ischemic or hemorrhagic stroke * History of moderate to severe TBI * History of or current psychosis not due to an external cause (e.g., due to illicit drug use) * Other neurological conditions (e.g., neurodegenerative disorders) * Active suicidal ideation with Columbia Suicide Severity Rating Scale(CSSRS) 3 * Are pregnant or nursing * Within 12 weeks of a major surgery/operation

Study locations

2 study locations are listed.

Site recruitment status is not specified in the registry data for these locations.

Countries: United States

  • Illinois, United States: 2

Sample of listed locations

  • Jesse Brown VA Medical Center, Chicago, IL — Chicago, Illinois, 60612, United States — Site recruitment status not specified in the registry data
  • Edward Hines Jr. VA Hospital, Hines, IL — Hines, Illinois, 60141-3030, United States — Site recruitment status not specified in the registry data

Study details

Start date
September 14, 2026
Primary completion date
June 1, 2031
First posted
September 8, 2025

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT07158567
Registry last updated
September 8, 2026
QualifiedStudies registry data refreshed
September 21, 2026

View NCT07158567 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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