Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis

NCT ID
NCT06998628
Registry status
Recruiting
Study type
Interventional
Phase
Phase 2
Sponsor
Tanta University
Conditions
Rheumatoid Arthritis

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Clinical Study Evaluating the Effect of Pentoxifylline as Anti Inflammatory in Patients With Rheumatoid Arthritis

Enrollment: 50 participants (Estimated).

What is being studied

  • Intervention: Aminopterin
  • Intervention: Heterocyclic Compounds
  • Intervention: Heterocyclic Compounds, 2-Ring
  • Intervention: Heterocyclic Compounds, Fused-Ring
  • Intervention: Methotrexate
  • Drug: Methotrexate
  • Intervention: Pentoxifylline
  • Drug: Pentoxifylline
  • Intervention: Pteridines
  • Intervention: Pterins
  • Intervention: Purines
  • Intervention: Purinones
  • Intervention: Theobromine
  • Intervention: Xanthines

Who may be eligible

Ages
18 Years to 70 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Patients with active rheumatoid arthritis (not in remission) according to American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) \[9\] i.e., 28 joints disease activity score (DAS 28) \>2.6. * Patients receiving the conventional DMARDs. * Both sexes. * Age range between 18and 70 years old Exclusion Criteria: * Patients with retinal or cerebral hemorrhage. * Patients with renal and hepatic dysfunction. * Patients with hypersensitivity to study medications. * Pregnant and lactating females. * Patients receiving biological or synthetic DMARDs

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: Egypt

  • Damietta Governorate, Egypt: 1

Sample of listed locations

  • Faculty of Medicine, Al-Azhar University — Damietta, Damietta Governorate, 34511, Egypt — Recruiting

Study details

Start date
June 2, 2025
Primary completion date
May 30, 2027
Completion date
September 30, 2027
First posted
May 31, 2025
Collaborators
Dr. Mustafa Adel Mustafa Elmenawy Lecturer of Rheumatology and Rehabilitation, Faculty of Medicine - El-Azhar University - Damietta

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT06998628
Registry last updated
October 5, 2026
QualifiedStudies registry data refreshed
October 12, 2026
QualifiedStudies record fetched
October 12, 2026

View NCT06998628 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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