Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
- NCT ID
- NCT06865170
- Registry status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Sponsor
- University of California, Davis
- Conditions
- Fear of Needles, Osteoarthritis (OA) of the Knee
Overview
ClinicalTrials.gov lists this study as Not yet recruiting.
Enrollment: 88 participants (Estimated).
What is being studied
- Procedure: +/- Ethyl Chloride Topical Aerosol Anesthetic
- Procedure: 22 gauge needle
- Procedure: 25 gauge needle
Who may be eligible
- Ages
- 40 Years to 89 Years
- Sex
- All
- Healthy volunteers accepted
- Yes
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
1. age ≥ 40 years
2. fulfillment of the American College of Rheumatology criteria for knee OA
3. confirmation of knee-related pain and/or functional loss by clinical examination.
4. Patients with either
1. bilateral knee OA/injections, or
2. unilateral knee OA/injections.
5. Agreed to an intra-articular knee joint injection with steroids
6. Naive to use of ethyl chloride
Exclusion Criteria:
1. Arthroscopy of the index knee(s) within the prior 6 months
2. Steroid injection of the knee(s) within the prior 3 months
3. Hyaluronic acid or platelet-rich plasma injection of the knee within the prior 6 months
4. Patient reported prior injection of any type with ethyl chloride spray
5. Knee effusion requiring aspiration at the time of the procedure
6. Cognitively impaired individuals
Study locations
1 study location is listed.
Site recruitment status is not specified in the registry data for these locations.
Countries: United States
- California, United States: 1
Sample of listed locations
- UC Davis Sports Medicine Clinic — Sacramento, California, 95817, United States — Site recruitment status not specified in the registry data
Study details
- Start date
- December 1, 2026
- Primary completion date
- December 1, 2026
- Completion date
- December 1, 2026
- First posted
- March 7, 2025
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT06865170
- Registry last updated
- September 16, 2026
- QualifiedStudies registry data refreshed
- October 5, 2026
- QualifiedStudies record fetched
- October 5, 2026
View NCT06865170 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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