MMA Embolization for Refractory Chronic Migraine

NCT ID
NCT06735833
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Conditions
Migraine Disorders

Overview

ClinicalTrials.gov lists this study as Recruiting.

Official title: Feasibility Study to Evaluate the Initial Safety and Effectiveness of TRUFILL n-BCA Liquid Embolic System in Middle Meningeal Artery Embolization for the Preventive Treatment of Refractory Chronic Migraine

Enrollment: 70 participants (Estimated).

What is being studied

  • Device: Middle Meningeal Artery embolization

Who may be eligible

Ages
18 Years to 65 Years
Sex
All
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Participant Inclusion Criteria, Candidates for this study must meet ALL the following inclusion criteria: 1. Patient is between 18 and 65 years of age (inclusive) at the time of consent 2. Age of onset of Chronic Migraine \<= 64 years 3. Age of onset of migraine diagnosis \< 50 years 4. Patient has a current diagnosis of refractory migraine 5. Patient has a current diagnosis of Chronic migraine Participant Exclusion Criteria, Candidates will be excluded from participation if ANY of the following apply: 1. Patients with a history for the last 2 years of other primary headache types, or secondary headache types except medication overuse headache 2. Patients with diagnosis of hemiplegic migraine or migrainous infarct 3. Patients with current regular use of Opioids, Cannabis, Medical Marijuana, etc 4. Women who are pregnant, lactating, or who are of childbearing age 5. Current involvement in an investigational (drug, device, etc.) clinical trial that may confound study endpoints. Participants in observational, natural history, and/or epidemiological studies not involving intervention are eligible. Sponsor approval is required

Study locations

8 study locations are listed.

Recruiting site status is explicitly provided for 8 locations; 8 are listed as Recruiting.

Countries: United States

  • California, United States: 1
  • Connecticut, United States: 1
  • New York, United States: 3
  • Pennsylvania, United States: 1
  • Tennessee, United States: 1
  • West Virginia, United States: 1

Sample of listed locations

  • John Muir Physician Network Clin. Research Center — Walnut Creek, California, 94598, United States — Recruiting
  • Hartford Hospital — Hartford, Connecticut, 06032, United States — Recruiting
  • University of Buffalo Medical Center — Buffalo, New York, 14203, United States — Recruiting
  • Mount Sinai — New York, New York, 10029, United States — Recruiting
  • Stony Brook University Medical Center — Stony Brook, New York, 11794, United States — Recruiting
  • Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, 19107, United States — Recruiting
  • Semmes Murphey Foundation — Memphis, Tennessee, 38120, United States — Recruiting
  • West Virginia University — Morgantown, West Virginia, 26506, United States — Recruiting

Study details

Start date
April 23, 2025
Primary completion date
December 25, 2026
Completion date
July 31, 2029
First posted
December 16, 2024

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT06735833
Registry last updated
September 25, 2026
QualifiedStudies registry data refreshed
October 5, 2026
QualifiedStudies record fetched
October 5, 2026

View NCT06735833 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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