Supraspinal Processing of Sensory Aspects of Pain
- NCT ID
- NCT05814497
- Registry status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Sponsor
- Children's Hospital Medical Center, Cincinnati
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Functional Abdominal Pain Syndrome, Migraine in Children, Musculoskeletal Pain
Overview
ClinicalTrials.gov lists this study as Recruiting.
Enrollment: 255 participants (Estimated).
What is being studied
- Other: Divided attention
- Other: Graphesthesia
- Other: Multisensory Task
Who may be eligible
- Ages
- 10 Years to 17 Years
- Sex
- All
- Healthy volunteers accepted
- Yes
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
* Patients will need a diagnosis of a chronic pain derived congruent with ICD-11 criteria related to headache (migraine, daily headache), abdominal (FAPD), localized MSK (single limb/joint, low back or chest pain), diffuse MSK (widespread MSK pain), or CRPS
* If on medications, they need to be on stable doses of prescribed pain and/or psychiatric medications for 4 weeks before the baseline study visit.
* Male or female, age 10 -17 (inclusive)
* English speaking, able to complete interviews and questionnaires in English
Exclusion Criteria:
* Weight/size incompatible with MRI scanner
* Orthodontic braces, metallic or electronic implants, or other metal objects in the body which obscure or interfere with the MRI, or pose a risk from heating, movement, or malfunction in the MRI environment
* Claustrophobia
* Youth who are pregnant
* Any comorbid rheumatic disease, diagnosis of epilepsy, other neurological diseases, or medical condition (e.g. diabetes, cancer, IBD)
* Present psychiatric disease as defined by DSM IV (e.g. psychosis, bipolar disorder, major depression, generalized anxiety disorder), alcohol or drug dependence, or documented developmental delays or impairments (e.g., autism, cerebral palsy, ADHD, or mental retardation) that, in the opinion of the investigator, would interfere with adherence to study requirements or safe participation in the study
* Skin conditions or past skin damage on the arms or legs in or near sites of sensory testing
* Outside the age range (9 years old or younger; 18 years or older) at the time of consent
* History of \> 1 month opioid treatment.
Study locations
1 study location is listed.
Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.
Countries: United States
- Ohio, United States: 1
Sample of listed locations
- Cincinnati Children's Hospital — Cincinnati, Ohio, 45229, United States — Recruiting
Study details
- Start date
- May 1, 2023
- Primary completion date
- June 30, 2027
- Completion date
- June 30, 2027
- First posted
- April 18, 2023
- Collaborators
- University of Barcelona
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT05814497
- Registry last updated
- June 5, 2026
- QualifiedStudies registry data refreshed
- October 2, 2026
- QualifiedStudies record fetched
- October 2, 2026
View NCT05814497 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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