Supraspinal Processing of Sensory Aspects of Pain

NCT ID
NCT05814497
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Children's Hospital Medical Center, Cincinnati
Conditions
Complex Regional Pain Syndromes, Fibromyalgia, Functional Abdominal Pain Syndrome, Migraine in Children, Musculoskeletal Pain

Overview

ClinicalTrials.gov lists this study as Recruiting.

Enrollment: 255 participants (Estimated).

What is being studied

  • Other: Divided attention
  • Other: Graphesthesia
  • Other: Multisensory Task

Who may be eligible

Ages
10 Years to 17 Years
Sex
All
Healthy volunteers accepted
Yes

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * Patients will need a diagnosis of a chronic pain derived congruent with ICD-11 criteria related to headache (migraine, daily headache), abdominal (FAPD), localized MSK (single limb/joint, low back or chest pain), diffuse MSK (widespread MSK pain), or CRPS * If on medications, they need to be on stable doses of prescribed pain and/or psychiatric medications for 4 weeks before the baseline study visit. * Male or female, age 10 -17 (inclusive) * English speaking, able to complete interviews and questionnaires in English Exclusion Criteria: * Weight/size incompatible with MRI scanner * Orthodontic braces, metallic or electronic implants, or other metal objects in the body which obscure or interfere with the MRI, or pose a risk from heating, movement, or malfunction in the MRI environment * Claustrophobia * Youth who are pregnant * Any comorbid rheumatic disease, diagnosis of epilepsy, other neurological diseases, or medical condition (e.g. diabetes, cancer, IBD) * Present psychiatric disease as defined by DSM IV (e.g. psychosis, bipolar disorder, major depression, generalized anxiety disorder), alcohol or drug dependence, or documented developmental delays or impairments (e.g., autism, cerebral palsy, ADHD, or mental retardation) that, in the opinion of the investigator, would interfere with adherence to study requirements or safe participation in the study * Skin conditions or past skin damage on the arms or legs in or near sites of sensory testing * Outside the age range (9 years old or younger; 18 years or older) at the time of consent * History of \> 1 month opioid treatment.

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: United States

  • Ohio, United States: 1

Sample of listed locations

  • Cincinnati Children's Hospital — Cincinnati, Ohio, 45229, United States — Recruiting

Study details

Start date
May 1, 2023
Primary completion date
June 30, 2027
Completion date
June 30, 2027
First posted
April 18, 2023
Collaborators
University of Barcelona

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT05814497
Registry last updated
June 5, 2026
QualifiedStudies registry data refreshed
October 2, 2026
QualifiedStudies record fetched
October 2, 2026

View NCT05814497 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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