Neurobiological Mechanisms of Aging and Stress on Prospective Navigation

NCT ID
NCT03896529
Registry status
Recruiting
Study type
Interventional
Phase
Not applicable
Sponsor
Georgia Institute of Technology
Conditions
Aging, Anxiety, Memory Impairment

Overview

ClinicalTrials.gov lists this study as Recruiting.

Enrollment: 85 participants (Estimated).

What is being studied

  • Behavioral: Anticipatory psychological stress

Who may be eligible

Ages
65 Years to 80 Years
Sex
All
Healthy volunteers accepted
Yes

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * adults 65-80 * U.S. citizens or permanent residents * who speak fluent English * willing to come to Georgia Tech to participate in group testing sessions. Exclusion Criteria: * Individuals will be carefully screened using IRB-approved procedures for safety contraindications to MRI and electrical shock stimulation * (e.g., metal or electrical implants, heart arrhythmia, or medication affecting the cardiovascular system \[e.g. beta-blockers\]). The purpose of this study is to investigate mechanisms of normally functioning memory, and memory-related changes in healthy aging. Thus, any confounding factors that may influence cognition, other than age, will be exclusionary. Potential participants that endorse any of the following conditions will be excluded from the study: * Epilepsy * Dementia * Parkinson's disease * history of stroke or seizure * psychiatric disorders * untreated depression or emotional conditions * Attention Deficit Disorder * Multiple Sclerosis * uncontrolled hyper- or hypo-tension * untreated Diabetes * Sickle Cell Anemia * regularly use illegal or psychoactive drugs (e.g., cocaine, alcohol abuse, etc). * Additionally, individuals scoring \< 3 on WAIS-R forward span, \< 2 on WAIS-R backward span, and failing to name more than 2 vegetable names will be excluded from the study. These exclusions will insure that persons with mild cognitive impairment or typical indications of clinical dementia will be not participate in the research.

Study locations

1 study location is listed.

Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.

Countries: United States

  • Georgia, United States: 1

Sample of listed locations

  • Center for Advance Brain Imaging — Atlanta, Georgia, 30318, United States — Recruiting

Study details

Start date
September 24, 2019
Primary completion date
December 25, 2026
Completion date
December 25, 2026
First posted
April 1, 2019
Collaborators
National Institute on Aging (NIA)

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT03896529
Registry last updated
September 23, 2026
QualifiedStudies registry data refreshed
September 28, 2026
QualifiedStudies record fetched
September 28, 2026

View NCT03896529 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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