Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
- NCT ID
- NCT03896529
- Registry status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Sponsor
- Georgia Institute of Technology
- Conditions
- Aging, Anxiety, Memory Impairment
Overview
ClinicalTrials.gov lists this study as Recruiting.
Enrollment: 85 participants (Estimated).
What is being studied
- Behavioral: Anticipatory psychological stress
Who may be eligible
- Ages
- 65 Years to 80 Years
- Sex
- All
- Healthy volunteers accepted
- Yes
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
* adults 65-80
* U.S. citizens or permanent residents
* who speak fluent English
* willing to come to Georgia Tech to participate in group testing sessions.
Exclusion Criteria:
* Individuals will be carefully screened using IRB-approved procedures for safety contraindications to MRI and electrical shock stimulation
* (e.g., metal or electrical implants, heart arrhythmia, or medication affecting the cardiovascular system \[e.g. beta-blockers\]).
The purpose of this study is to investigate mechanisms of normally functioning memory, and memory-related changes in healthy aging. Thus, any confounding factors that may influence cognition, other than age, will be exclusionary. Potential participants that endorse any of the following conditions will be excluded from the study:
* Epilepsy
* Dementia
* Parkinson's disease
* history of stroke or seizure
* psychiatric disorders
* untreated depression or emotional conditions
* Attention Deficit Disorder
* Multiple Sclerosis
* uncontrolled hyper- or hypo-tension
* untreated Diabetes
* Sickle Cell Anemia
* regularly use illegal or psychoactive drugs (e.g., cocaine, alcohol abuse, etc).
* Additionally, individuals scoring \< 3 on WAIS-R forward span, \< 2 on WAIS-R backward span, and failing to name more than 2 vegetable names will be excluded from the study. These exclusions will insure that persons with mild cognitive impairment or typical indications of clinical dementia will be not participate in the research.
Study locations
1 study location is listed.
Recruiting site status is explicitly provided for 1 location; 1 is listed as Recruiting.
Countries: United States
- Georgia, United States: 1
Sample of listed locations
- Center for Advance Brain Imaging — Atlanta, Georgia, 30318, United States — Recruiting
Study details
- Start date
- September 24, 2019
- Primary completion date
- December 25, 2026
- Completion date
- December 25, 2026
- First posted
- April 1, 2019
- Collaborators
- National Institute on Aging (NIA)
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT03896529
- Registry last updated
- September 23, 2026
- QualifiedStudies registry data refreshed
- September 28, 2026
- QualifiedStudies record fetched
- September 28, 2026
View NCT03896529 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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