Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
- NCT ID
- NCT03759522
- Registry status
- Recruiting
- Study type
- Not specified in the registry data
- Phase
- Phase 1
- Sponsor
- University of Alabama at Birmingham
Overview
ClinicalTrials.gov lists this study as Recruiting.
Enrollment: 120 participants (Estimated).
What is being studied
No interventions are listed in the registry data.
Who may be eligible
- Ages
- Not specified in the registry data
- Sex
- Not specified in the registry data
- Healthy volunteers accepted
- Yes
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
1. 18 to 65 years of age
2. Healthy volunteer OR Clinical diagnosis of Multiple Sclerosis (MS) OR Meets 2016 American College of Rheumatology (ACR) case definition criteria for fibromyalgia OR Meets 1994 Fukuda case definition criteria for Chronic Fatigue Syndrome
Exclusion Criteria:
1. Contraindication to MRI
2. Pregnancy
3. Lactation
4. Individuals who are unable to participate in the imaging portion due to severity of their medical condition
5. Chronic infectious disease (e.g. HIV, HCV)
6. Viral or bacterial illness requiring medical attention and/or antibiotics within 1 month of study participation
7. Diagnosis of cancer, including leukemia
8. Blood or blood clotting disorder
9. Except for individuals with MS, a diagnosis of autoimmune disease is exclusionary
10. Positive urine β-hCG test day of procedure or a serum -hCG test within 48 hours prior to the administration of \[18F\]DPA-714
11. Currently enrolled in a clinical trial utilizing experimental therapies
Study locations
1 study location is listed.
Site recruitment status is not specified in the registry data for these locations.
Countries: United States
- Alabama, United States: 1
Sample of listed locations
- University of Alabama at Birmingham Medical Center — Birmingham, Alabama, 35294, United States — Site recruitment status not specified in the registry data
Study details
- Start date
- February 3, 2019
- Primary completion date
- April 1, 2028
- First posted
- November 30, 2018
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT03759522
- Registry last updated
- June 2, 2026
- QualifiedStudies registry data refreshed
- September 21, 2026
View NCT03759522 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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