Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes

NCT ID
NCT03264352
Registry status
Recruiting
Study type
Not specified in the registry data
Phase
Phase 4
Sponsor
XueQing Yu

Overview

ClinicalTrials.gov lists this study as Recruiting.

Enrollment: 11414 participants (Estimated).

What is being studied

No interventions are listed in the registry data.

Who may be eligible

Ages
Not specified in the registry data
Sex
Not specified in the registry data
Healthy volunteers accepted
No

ClinicalTrials.gov lists the following eligibility criteria.

Inclusion Criteria: * irrespective of sex; * aged between 45 and 79 years; * with office-measured seated BP 120-139 mm Hg systolic and below 90 mm Hg diastolic; * diagnosed of type 2 diabetes mellitus (T2DM), currently on diabetic therapy; * informed consent provided and long-term follow-up possible Exclusion Criteria: * poor control of blood glucose, HbA1c \> 10.0% * administration of any antihypertensive medications within 1 month; * a history of hypoglycemic coma / seizure; * confirmed diagnosis of type 1 diabetes mellitus; * alanine-aminotransferase (ALT) or aspartate-aminotransferase (AST) over three times the upper limit of normal; * estimated glomerular filtration rate \< 45 ml/min/1.73m2; * a history of congestive heart failure with left ventricular ejection fraction \< 40%; * coronary artery disease requiring RAS blockers for secondary prevention; * acute on-set of stroke within 6 months prior to randomization; * a ratio of urinary albumin (in mg/L) to urinary creatinine (in g/L) (ACR) ≥ 300 mg/g; * known contraindications for the active study medications; * a history of psychological or mental disorder; * pregnancy or currently planning to have babies or lactation; * severe diseases such as severe heart diseases; * an expected residual life span less than 3 years; * a malignancy that clinical investigators consider as unsuitable to participate; * currently participating in another clinical trial.

Study locations

1 study location is listed.

Site recruitment status is not specified in the registry data for these locations.

Countries: China

  • Guangdong, China: 1

Sample of listed locations

  • Guangdong General Hospital — Guangzhou, Guangdong, 501080, China — Site recruitment status not specified in the registry data

Study details

Start date
February 1, 2018
Primary completion date
September 1, 2028
First posted
August 29, 2017

Source and update information

Source
ClinicalTrials.gov
NCT ID
NCT03264352
Registry last updated
September 14, 2026
QualifiedStudies registry data refreshed
September 21, 2026

View NCT03264352 on ClinicalTrials.gov

Trial information can change. Confirm current study details with the study team or the registry.

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