Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes
- NCT ID
- NCT03264352
- Registry status
- Recruiting
- Study type
- Not specified in the registry data
- Phase
- Phase 4
- Sponsor
- XueQing Yu
Overview
ClinicalTrials.gov lists this study as Recruiting.
Enrollment: 11414 participants (Estimated).
What is being studied
No interventions are listed in the registry data.
Who may be eligible
- Ages
- Not specified in the registry data
- Sex
- Not specified in the registry data
- Healthy volunteers accepted
- No
ClinicalTrials.gov lists the following eligibility criteria.
Inclusion Criteria:
* irrespective of sex;
* aged between 45 and 79 years;
* with office-measured seated BP 120-139 mm Hg systolic and below 90 mm Hg diastolic;
* diagnosed of type 2 diabetes mellitus (T2DM), currently on diabetic therapy;
* informed consent provided and long-term follow-up possible
Exclusion Criteria:
* poor control of blood glucose, HbA1c \> 10.0%
* administration of any antihypertensive medications within 1 month;
* a history of hypoglycemic coma / seizure;
* confirmed diagnosis of type 1 diabetes mellitus;
* alanine-aminotransferase (ALT) or aspartate-aminotransferase (AST) over three times the upper limit of normal;
* estimated glomerular filtration rate \< 45 ml/min/1.73m2;
* a history of congestive heart failure with left ventricular ejection fraction \< 40%;
* coronary artery disease requiring RAS blockers for secondary prevention;
* acute on-set of stroke within 6 months prior to randomization;
* a ratio of urinary albumin (in mg/L) to urinary creatinine (in g/L) (ACR) ≥ 300 mg/g;
* known contraindications for the active study medications;
* a history of psychological or mental disorder;
* pregnancy or currently planning to have babies or lactation;
* severe diseases such as severe heart diseases;
* an expected residual life span less than 3 years;
* a malignancy that clinical investigators consider as unsuitable to participate;
* currently participating in another clinical trial.
Study locations
1 study location is listed.
Site recruitment status is not specified in the registry data for these locations.
Countries: China
- Guangdong, China: 1
Sample of listed locations
- Guangdong General Hospital — Guangzhou, Guangdong, 501080, China — Site recruitment status not specified in the registry data
Study details
- Start date
- February 1, 2018
- Primary completion date
- September 1, 2028
- First posted
- August 29, 2017
Source and update information
- Source
- ClinicalTrials.gov
- NCT ID
- NCT03264352
- Registry last updated
- September 14, 2026
- QualifiedStudies registry data refreshed
- September 21, 2026
View NCT03264352 on ClinicalTrials.gov
Trial information can change. Confirm current study details with the study team or the registry.
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